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Suzetrigine

API

CAS Number

2649467-58-1

Molecular Formula

C21H20F5N3O4

Product format

Neat

Molecular Weight

473.40

API Family

Suzetrigine

Synonyms

Suzetrigine; 2649467-58-1; VX-548; JOURNAVX; VXC-548; VRT-1737548; LOG73M21H5; 4-[[(2R, 3S, 4S, 5R)-3-(3, 4-difluoro-2-methoxyphenyl)-4, 5-dimethyl-5-(trifluoromethyl)oxolane-2-carbonyl]amino]pyridine-2-carboxamide; 4-(((2R, 3S, 4S, 5R)-3-(3, 4-difluoro-2-methoxyphenyl)-4, 5-dimethyl-5-(trifluoromethyl)oxolane-2-carbonyl)amino)pyridine-2-carboxamide; RefChem:1099300; Suzetrigina; VX548; 4-((2R, 3S, 4S, 5R)-3-(3, 4-Difluoro-2-Methoxyphenyl)-4, 5-Dimethyl-5-(Trifluoromethyl)Tetrahydrofuran-2-Carboxamido)Picolinamide; 4-[(2R, 3S, 4S, 5R)-3-(3, 4-Difluoro-2-methoxyphenyl)-4, 5-dimethyl-5-(trifluoromethyl)oxolane-2-amido]pyridine-2-carboxamide; 4-[[[(2R, 3S, 4S, 5R)-3-(3, 4-Difluoro-2-methoxyphenyl)tetrahydro-4, 5-dimethyl-5-(trifluoromethyl)-2-furanyl]carbonyl]amino]-2-pyridinecarboxamide; suzetriginum; Journavx (TN); 4-[(2R, 3S, 4S, 5R)-3-(3, 4-Difluoro-2-methoxyphenyl)-4 and 5-dimethyl-5-(trifluoromethyl)tetrahydrofuran-2-carboxamido]picolinamide; suzetrigine [INN]; Suzetrigine [WHO-DD]

Iupac Name

4-[[(2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)oxolane-2-carbonyl]amino]pyridine-2-carboxamide

InChI

InChI=1S/C21H20F5N3O4/c1-9-14(11-4-5-12(22)15(23)16(11)32-3)17(33-20(9,2)21(24,25)26)19(31)29-10-6-7-28-13(8-10)18(27)30/h4-9,14,17H,1-3H3,(H2,27,30)(H,28,29,31)/t9-,14-,17+,20+/m0/s1


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Synthesis

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